Sessions:101-110


101. SIB Special Invited Session: “Statistics in Genomics”

Organizer and Chair: Hongkai Ji, Johns Hopkins University, Email: hji@jhu.edu

Speaker 1: Hui Jiang, University of Michigan, Email:  jianghui@umich.edu
Title: Robust Modeling of RNA Sequencing Data

Speaker 2: Jingyi Li, University of California, Los Angeles, Email: jli@stat.ucla.edu 
Title: Statistical Inference Problems Arising from the Availability of Multiple RNA­seq
Data Sets

Speaker 3: Wenxiu Ma, University of California, Riverside, Email: wenxiu.ma@ucr.edu

Title: DNA sequence+shape kernel enables alignment-free modeling of transcription factor binding

Speaker 4: Zhaohui Qin, Emory University, Email: zhaohui.qin@emory.edu 
Title: Improving Bayesian Hierarchical Models Using External Data

102. Recent Topics on Extreme Values

Organizer and Chair: Deyuan Li, Fudan University, Email: deyuanli@fudan.edu.cn

Speaker 1: Taizhong Hu, University of Science and Technology of China,
Email: thu@ustc.edu.cn
Title:  Asymptotic Expansions of Generalized Quantiles and Expectiles for Extreme Risks

Speaker 2: Jinguan Lin, Southeast University, China, Email: jglin@seu.edu.cn 
Title: Bootstrap Jump Test Time-varying Coefficient Regression Models and Empirical Analysis

Speaker 3: Zhengjun Zhang, University of Wisconsin at Madison, Email: zjz@stat.wisc.edu
Title: Extreme Value Data Analytic Approach for Large Scale Optimization

Speaker 4: Chen Zhou, De Nederlandsche Bank and Erasmus University Rotterdam, Netherlands, Email: c.zhou@dnb.nl

Title: Estimating Systematic Risk under Extremely Adverse Market Conditions

103. Recent Development in Multiple Testing and Post Selection Inference in
High- Dimensional Regression 

Organizer: Xinping Cui, University of California, Riverside, Email: xinping.cui@ucr.edu

Chair: Bushi Wang, Boehringer Ingelheim Pharmaceuticals, 
Email: bushi.wang@boehringer-ingelheim.com

Speaker 1: Jason Hsu, Eli Lilly & Company, Email: jch@stat.osu.edu

Title: Statistical Limitation of GWAS to Discover SNPs That Are Causal

Speaker 2: Helmut Finner, German Diabetes Center, Düsseldorf Email: Helmut.Finner@DDZ.uni-duesseldorf.de
Title:  From higher criticism and local levels of GOF tests to confidence bounds for the proportion of true nulls

Speaker 3: Zhigen Zhao, Temple University, Email: zhaozhg@temple.edu

Title: Rate Optimal Multiple Testing Procedure in High-dimensional Regression

Speaker 4: Xinping Cui, University of California, Riverside, Email: xinping.cui@ucr.edu

Title: Sequential Multiple Testing for Variable Selection in High Dimensional Linear Model


104. Recent Advances on MM Algorithms

Organizer: Hua Zhou, University of California at Los Angeles, Email: huazhou@ucla.edu

Chair: Gary Guoliang Tian, The University of Hong Kong, Email: gltian@hku.hk

Speaker 1: Eric Chi, North Carolina State University, Email: eric_chi@ncsu.edu

Title: An MM algorithm for the Split-Feasibility Problem

Speaker 2: Yin Liu, Zhongnan University of Economics and Law, Email: yliu_1031@sina.com

Title: A Novel MM Algorithm and the Mode-Sharing Method in Bayesian Computation for the
Analysis of General Incomplete Categorical Data

Speaker 3: Joshua Day, North Carolina State University, Email: jtday2@ncsu.edu

Title: Online MM Algorithms for Statistical Learning

Speaker 4: Hua Zhou, University of California at Los Angeles, Email: huazhou@ucla.edu

Title: MM Algorithms for Variance Components Models

Speaker 5: Xi-Fen Huang, The University of Hong Kong, Email: u3003396@connect,hku.hk
Title: A Unified Decomposition, Minorization and Assembly (DMS) Techniques for Constructing Separable Minorizing Functions in a Class of MM Algorithms

105. Recent Statistical Advances and Challenges in Cancer Studies

Organizer and Chair: Yiyi Chen, Oregon Health and Science University,
Email: chenyiy@ohsu.edu

Speaker 1: Simon Noah, University of Washington, Email: nrsimon@u.washington.edu

Title: Adaptive Enrichment Trials for Biomarker-guided Treatments

Speaker 2: Byung Park, Oregon Health and Science University, Email: parkb@ohsu.edu

Title: Fiducial Inference on a Biomarker Adaptive Design

Speaker 3: Jessica Minnier, Oregon Health and Science University, Emaill: minnier@ohsu.edu

Title: Colorectal Cancer Risk Classification with Genetic and Environmental Data via Kernel
Machine Methods

Speaker 4: Yiyi Chen, Oregon Health and Science University, Email: chenyiy@ohsu.edu

Title: An Adaptive Bayesian Sequential Design for Determining the Subject-Specific Optimal Treatment Length

106. Challenges to Statistical Issues in Complex Clinical Trials

Organizers: Chin-Fu Hsiao, National Health Research Institute, Taiwan, Email: chinfu@nhri.org.tw, and Toshimitsu Hamasaki, National Cerebral and Cardiovascular Center, Japan, 

Email: toshi.hamasaki@ncvc.go.jp
Chair: Chin-Fu Hsiao, National Health Research Institute, Taiwan, Email: chinfu@nhri.org.tw

Speaker 1: Lingyun Liu, Cytel Inc., Email: Lingyun.Liu@cytel.com

Title: An Adaptive Enrichment Design with Sample Size Re-estimation--A Case Study

Speaker 2: Dong Xi, Novartis, Email: dong.xi@novartis.com

Title: Power and Sample Size Calculation Using Graphical Approaches

Speaker 3: Toshimitsu Hamasaki, National Cerebral and Cardiovascular Center, Japan,
 Email: toshi.hamasaki@ncvc.go.jp

Title: Interim Evaluation of Efficacy or Futility in Group-Sequential Clinical Trials with
Multiple Co-Primary Endpoints

Speaker 4: Cui Lu, Abbvie Inc. Email address: lu.cui@abbvie.com 

Title: Improvement of Seamless Phase 2/3 Trial Based on Continuous Outcome

107. Challenges to Statistical Issues in Multiregional Clinical Trials

Organizers: Chin-Fu Hsiao, National Health Research Institute, Taiwan, Email: chinfu@nhri.org.tw, and Toshimitsu Hamasaki, National Cerebral and Cardiovascular Center, Japan, Email: toshi.hamasaki@ncvc.go.jp, and 
Chair: Toshimitsu Hamasaki, National Cerebral and Cardiovascular Center, Japan,
Email: toshi.hamasaki@ncvc.go.jp

Speaker 1: Yuki Ando, PMDA, Japan, Email: ando-yuki@pmda.go.jp

Title: Regulatory and Statistical Issues of Multi-regional Clinical Trials

Speaker 2: Seung-Ho Kang, Yonsei University, Korea, Email: seungho@yonsei.ac.kr

Title: New Perspective on the Determination of the Number of Japanese Patients in
Multiregional Clinical Trials

Speaker 3: Gang Chen, Johnson and Johnson, Email: gchen11@ITS.JNJ.com

Title: MRCT – Consistency Assessment and Sample Size

Speaker 4: Luyan Dai, Boehringer Ingelheim Pharmaceuticals, Inc.
Email: luyan.dai@boehringer-ingelheim.com
Title: Scientific Issues Regarding MRCT and Use of Foreign Data – Asian Perspectives

108. New Methods for Large Graphical Models and Genetic Data

Organizer: Zheng Tracy Ke, University of Chicago, Email: zke@galton.uchicago.edu

Chair: Fang Han, Johns Hopkins University, Email: fhan@jhu.edu

Speaker 1: Lucy Xia, Stanford University, Email: lucyxia@stanford.edu

Title: A Conditional Dependence Measure with Applications to Undirected Graphical Models

Speaker 2: Xin He, University of Chicago, Email: xinhe@uchicago.edu

Title: Estimating Genome-wide Mutation Rates using Poisson Mixed Effect Model

Speaker 3: Yingying Wei, Chinese University of Hong Kong, Email: yweicuhk@gmail.com

Title: Scalable Nonparametric Bayes Learning of Heterogeneous Dynamic Poisson Graphical Models

Speaker 4: Zheng Tracy Ke, University of Chicago, Email: zke@galton.uchicago.edu

Title: Detecting Rare and Weak Spikes in Large Covariance Matrices

109. Caveats, Challenges, and Opportunities for Indirect Comparisons
Using Clinical Trial Data

Organizer: James Pan, Johnson & Johnson, Email: jpan3@its.jnj.com 

 Chair: Zhong Yuan, Janssen R&D, Email: zyuan6@its.jnj.com

Speaker 1: Bin (Eddy) Jia, Johnson & Johnson (QS China), Email: bjia33@its.jnj.com

Title:  Meta-analysis of Efficacy and Safety of the New Anticoagulants Versus Warfarin in Patients with Atrial Fibrillation

Speaker 2: Zhong Yuan, Janssen R&D, Email:  zyuan6@its.jnj.com

Title:  Comparison of Time in Therapeutic Range for Warfarin Therapy in Contemporary 
 Clinical Trials of Patients with Atrial Fibrillation

Speaker 3: Leslie Meng, Amgen Asia R&D, Email, xianhuam@amgen.com
 Title:  Confounder Adjustment on Treatment Effect When Using Observational Study as Control

Discussant: Jesse Berlin, Senior Vice President, Johnson & Johnson, Email: JBerlin@its.jnj.com

110. Recent Advances in Robust High-Dimensional Estimation and Inference

Organizer: Zhao Ren, University of Pittsburgh, Email: zren@pitt.edu

Chair: Mengjie Chen, University of North Carolina at Chapel Hill,Email:mengjie@email.unc.edu

Speaker 1: Cun-Hui Zhang, Rutgers University, Email: czhang@stat.rutgers.edu

Title: High-Dimensional Regression under Low-Moment Conditions on Random Designs

Speaker 2: Fang Han, University of Washington, Email: johnfhan@gmail.com

Title: On Some New Advances in Exploiting and Understanding Kendall's tau

Speaker 3: Chao Gao, Yale University, Email: chao.gao@yale.edu

Title: A General Decision Theory for Huber's ε-Contamination Model

Speaker 4: Zhao Ren, University of Pittsburgh, Email: zren@pitt.edu

Title: Robust Covariance/Scatter Matrix Estimation via Matrix Depth